ADULT NEUROGENESIS AND NEURODEGENERATIVE DISEASES
Acronimo: ANND
Tipo: Grupo emergente
Email:
Categorías: LS5 Neuroscience and Neural Disorders
BMED Biomedicina
Coordinador:
Miembros:
Enlaces:
Lineas de investigación:
NEUROGÉNESIS ADULTA ENFERMEDADES NEURODEGENERATIVAS NEUROPROTECCIÓN ACTIVIDAD FÍSICA Y ENRIQUECIMIENTO AMBIENTAL INFLAMACIÓN ESTRÉS Y DEPRESIÓN
Proyectos más relevantes:
– Spanish Ministry of Economy and Competitiveness: Ramón y Cajal contract RYC-2015-17189. Starting date: 01/01/2017. Country: Spain. PI: Dr. María Llorens-Martín. – The Alzheimer´s Association 2017 Research Grant, AARG-17-528125. “Novel methods to interrogate the subcellular machinery of AD models in vivo”. This Research Grant was awarded on August 23, 2017, and there is no grant number associated with it yet. Country: USA. PI: Dr. María Llorens-Martín. – The Association for Frontotemporal Degeneration (AFTD)’s 2016 Basic Research Pilot Grant. Starting date: 01/01/2017. “Tau and adult neurogenesis. Therapeutic potential for frontotemporal degeneration.” Country: USA. PI: Dr. María Llorens-Martín. – The Alzheimer´s Association 2015 New Investigator Research Grant: 2015-NIRG-340709, “GSK-3ß and adult neurogenesis. therapeutic potential for AD.” Starting date: 06/01/2015. Country: USA. PI: Dr. María Llorens-Martín.
Publicaciones más relevantes:
1) Llorens-Martín M, Fuster-Matanzo A, Teixeira CM, Jurado-Arjona J, Ulloa F, Defelipe J, Rábano A, Hernández F, Soriano E, Avila J. Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice. Mol Psychiatry. 2013 Apr;18(4):395. Impact Factor: 14.9 2) Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis. Pallas-Bazarra N, Jurado-Arjona J, Navarrete M, Esteban JA, Hernández F, Ávila J, Llorens-Martín M. EMBO J. 2016 Jul 1; 35 (13) :1417 – 36. Impact Factor: 10,434. 3)Absence of microglial CX3CR1 impairs the synaptic integration of adult-born hippocampal granule neurons. Bolós M; Perea JR; Terreros-Roncal J; Pallas-Bazarra N; Jurado-Arjona J, Ávila J; Llorens-Martín M. Brain Behav Immun. In press. Impact Factor: 5,91. 4)Llorens-Martín M, Tejeda GS, Trejo JL. Antidepressant and proneurogenic influence of environmental enrichment in mice. Neuropsychopharmacology. Nov;36(12):2460-8. Impact Factor: 8.7